Describing the intestinal microbiota of Holstein Fasciola-positive and -negative cattle from a hyperendemic area of fascioliasis in central Colombia

The ability to identify compositional changes in the intestinal microbiota of parasitized hosts is important for understanding physiological processes that may affect animal productivity. Within field host–parasite interactions, many studies have suggested helminths can influence microbial composition their via immunomodulatory effects. Bovine fascioliasis a helminthiasis widely studied by immunologists, but with little information available regarding gut communities. Thus, we aimed describe Holstein Fasciola -positive and -negative cattle using parasitological methods ELISA (enzyme-linked immunosorbent assay). fecal samples (n = 65) were obtained from livestock slaughter plants Cundi-Boyacense Colombian highlands (a hyperendemic region bovine fascioliasis) amplicon-based next-generation 16S-rRNA 18S-rRNA gene sequencing. From these samples, 35 hepatica and, 30 F . our detection analysis. Our results showed reduction relative abundance Bacteroidetes Ascomycota along decreased abundances commensal taxa previously associated fermentation digestion processes. However, metabolomic approaches functional analyzes are necessary support hypothesis. These findings small first step development research at how populations bovines modulated liver helminth infections.